Reproducible Science

With the manuscript, someone can…

• Reproduce an experiment
• Generate new data
• Repeat the data analysis
• Draw the same conclusions

Repeatable Science

With the data and source code, someone can…

• Repeat the analysis
• Reproduce the same results
• The analysis is repeatable by yourself
• Hopefully repeatable by others as well!

Reproducible and Repeatable

Science is built on reproducible experiments.

Reproducible experiments requires repeatable analyses.

To Repeat an Analysis

• Requires data (Open Science)
• Requires tools (Open Source)

Homebrew

Linuxbrew

Linuxbrew

• Install software packages where you want
• Takes care of recursive dependencies
• No need for root access or sudo
• Use the same package manager on your
  Mac laptop and Linux server
• Supports any Linux distribution from the last decade
• Easily install recent versions of gcc and glibc
  in your home directory

Linuxbrew

• Up-to-date software, including bioinformatics
• Install precompiled binary packages or from source
• Install an entire pipeline of tools from a given date
  in the past (future not yet supported)

Homebrew Science

Community

• Maintained by a fervent community of
  maintainers and contributors
• 250 bioinformatics packages and 110 contributors
• 600 science packages and 450 contributors
• 3,600 core packages and 5,700 contributors
• 4,400 active Linuxbrew users in 30 days

Conclusion

• Open Science and Open Source are critical components of reproducible science
• Linuxbrew streamlines the repeatable installation of software tools

brew install good-science

Thanks to all the maintainers and contributors of Homebrew, Linuxbrew and Homebrew-Science!